Press and Accolades

• On the occasion of the 15th anniversary of the founding of the journal, Disease Models and Mechanisms, Guy Caldwell contributed an invited editorial on the preclinical utility of C. elegans, bookending a piece he and Kim Caldwell had published for the inaugural issue of DMM.
• In collaboration with the lab of James Shorter at Univ. Pennsylvania, we published research in Molecular Cell extend previously exciting findings on the use of protein engineering to generate a tunable chaperone protein to combat protein misfolding in neurodegenerative disease models.
• Dial for tuning dopamine, environmental signals found in Parkinson’s – Led by former Worm Shack M.S. students, Brucker Nourse and Shannon Russell, this team of all student researchers discover an exciting interface between dopaminergic and epigenetic modulation that simultaneously defines the molecular mechanism through which Parkinson’s occurs in specific patients.  This research appears in the prestigious journal, Proceedings of the National Academy of Sciences, and is the 7th time our students have published in PNAS!
• Worm Shack researchers, led by newly minted Dr. Anthony Gaeta, with the invaluable contributions of other Wormshackers, publish an exciting connection between the organismal regulatory mechanism for small RNA transport and dopamine neuron survival in PLoS Genetics to reveal a previously unreported mechanism for neuroprotection, as well as several new therapeutic targets for Parkinson’s disease.
• The future of personalized and precision medicine includes C. elegans! Well, at least according to a wonderful invited article written by lead author and Wormshacker, Melanie Mew, in the 2022 Review Issue of the Oxford University Press journal, Human Molecular Genetics.
• Guy Caldwell named Watkins Visiting Professor at Wichita State University, joining past honorees Linus Pauling, Melvin Calvin, Jane Goodall, Stephen J. Gould, and others. Yes, it remains a Shocker that he was selected! 
• Guy and Kim Caldwell among an international team of scientists who have discovered potential therapeutic molecules for Alzheimer’s disease using Artificial Intelligence – and worms, of course!  Check out the paper in Nature Biomedical Engineering led by outstanding collaborators at the University of Oslo.
• Findings from The Worm Shack back in 2008 unite human geneticists, clinicians, and other scientists from The Netherlands,  Canada – and Alabama, to the uncover a new genetic cause of neurodegeneration and define a novel movement disorder found in patients (published in EMBO Molecular Medicine).
• Worm Shack doctoral candidate, Jennie “Showtime!” Thies, receives an independent and prestigious R36 Diversity Fellowship grant from the NIH to support herself and her research into Parkinson’s disease.
• Worm Shack undergrad researcher, Madeline Vaji, publishes two different MicroPublications on methods to study epilepsy in worms. 
• Shack research team publishes new suite of Alzheimer’s models to investigate interactions between ApoE and amyloid-beta in C. elegans.
• New paper on Alzheimer’s and Parkinson’s published as cover story of Human Molecular Genetics, cover art from primary author, Ed Griffin
• Caldwell Lab awarded new grant from the NIH to explore resilience to Parkinson’s disease
• Wormshackers Rylee Perentis, Logan Norris, and Blake Parker honored as 2018 Randall Outstanding Undergraduate Research Award recipients
• Lauren Cook and Nathan Moniz both place 2nd, for poster and oral, respectively, at College of Arts & Sciences Undergrad Research Summit
• Two students (Brucker Nourse and Lacey Kennedy) co-author online commentaries on articles published in Disease Models an Mechanisms 
• Brucker Nourse honored with top GTA departmental award on 2018 Honors Day
• UA Press Release: on article co-authored by collaborators at the Univ. of Pennsylvania, Hanna Kim and the Shack in Nature Neuroscience revealing the mechanism by which dopamine influences neurodegneration in Parkinson’s disease
• Nature – Careers: Feature on Worm Shack’s own Dr. Laura Berkowitz’s Career Path
• UA Press Release: UA Scientists Identify Metabolic Link between Aging, Parkinson’s in Cell Metabolism article
• UA Press Release: Lipid Deficiency Linked to Neuron Degeneration in study published with co-authors from LSU Medical Center in Shreveport in the Proceedings of the National Academy of Sciences
• Reprogrammed Protein Shows Neurologic Diesease Treatment Promise in UA research published in Cell.
• Tuscaloosa News: UA team part of major breakthrough research on Parkinson’s disease published in Science.
• Science Daily Press Release: Gaining Insight Into a Gene’s Protective Role in Parkinson’s; published in Cell
• A Step Toward Unraveling Alzheimer’s Disease, Scientists outline a new method for understanding Alzheimer’s disease in Science paper
• Science Daily Press Release, Rare Genetic Disorder Provides Unique Insight Into Parkinson’s Disease
• Harvard, UA Researchers Hone in on a Protein’s Precise Role in Disease Prevention
• Worm Shack undergraduates chosen as Dystonia, Parkinson’s Scholars
• Caldwell lab publishes drug discovery lead for movement disorder
• Brain Science Podcast interview with Guy Caldwell about his career and research in The Worm Shack
• MIT Press Release on collaborative paper with the Lindquist lab published in Nature Chemical Biology on use of cyclic peptides as a therapeutic strategy for neurodgenerative disease
• 2008 Nobel Prize in Chemistry Awarded to Martin Chalfie, December 2008 (Guy Caldwell’s Postdoc Sponsor). Check out the
  Nobel Organization Official Brochure with image from The Caldwell Lab!
• Caldwell named part of scientific “Dream Team” to combat Parkinson’s
• ​HHMI Press Release, Howard Hughes Medical Institute Collaborative Innovation Award to Guy Caldwell and colleagues
• UA Press Release, Caldwells Named Recipients of Blackmon-Moody Award, the top faculty award at UA, November 2008
• Caldwells named inaugural recipients of the HudsonAlpha Innovation Prize, April 2008
• HHMI Press Release, story about our research into Parkinson’s Disease in collaboration with Dr. Susan Lindquist and others
• HHMI Bulletin feature story about the success of undergraduate researchers in The Worm Shack
• Article published in The Journal of Neuroscience defines neuroprotective capacity of movement disorder protein
• Science magazine, CarpeDB featured in NetWatch, Feb. 25, 2005
• HHMI Press Release, story about worm model for epilepsy and lissencephaly
• Science magazine story about our research into movement disorders
• Biophotonics International, feature story on our research, “Prospects in Medicine”
• American Society for Cell Biology, 2003 Press Book, feature on our epilepsy research
• HHMI Press Release, story about our research into dystonia,